Year Graduated: 2006

Student's Name Thesis Advisor(s) List of Published Papers During Study Time
**Equally Contributing Authors
* Corresponding Author(s)
Rey-Ting Guo x Dr. Andrew H.-J. Wang
  1. Guo, R. T., Cao, R., Ko, T. P., Chang, T.H.,Jeng, W.Y.,Kuo, C.J., Chen, C. K.-M., Hudock, M. P., Zhang, Y., Song, Y., Liang, P.H.,Oldfield, E., and Wang, A.H.-J.(2007)Bisphosphonates target mulitiple sites in both cis- and trans-prenyltransferases. Proc. Natl. Acad. Sci. USA104, 10022-10027.
  2. Chang, T. H., Guo, R. T., Ko, T. P., Wang, A. H.-J., and Liang, P. H. (2006) Crystal structure of type- geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination. J. Biol. Chem. 281,14991-15000.
  3. Sun, H. Y., Ko, T.P., Kuo, C.J., Guo, R. T., Chou, C. C., Liang, P.H., and Wang, A.H.-J. (2005)Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures. J Bacteriol. 187, 8137-8148.
  4. Guo, R. T., Ko, T. P., Chen, A.P.-C. Kuo, C. J., Wang, A. H. VJ., and Liang, P.H. (2005) Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate and farnesyl thiopyrophosphate:Roles of the metal ion and conserved residues in catalysis. J.Biol. Chem. 280, 20762-20774.
  5. Chu, H. M*., Guo, R. T., Lin T. W., Chou, C. C., Shr, H. L., Lai, H.L., Tang, T. Y., Cheng, K. J. Selinger, B. L., and Wang, A. H.-j. (2004) Structures of Selenomonas ruminantium Phytase in complex with persulfated phytate: DSP phytase fold and mechanism for sequential substrate hydrolysis. Structure. 12,2015-2024.
  6. Guo, R. T., Kuo, C. J., Ko, T. P., Chou, C. C., Liang, P. H., and Wang, A. H.-J. (2004) A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long-chain trans-prenyl products. Biochemistry. 43, 7678-7876.
  7. Guo, R. T., Kuo, C. J., Ko, T. P., Chou, C. C., Ko, T. P., Shr, H. L., Liang, P. H., and Wang, A. H.-J. (2004) Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritime and mechanism of product chain length determination. J. Biol. Chem. 279, 4903-4912.
  8. Guo, R. T., Ko, T. P., Chou, C. C., Shr, H.L., Chu, H. M., Tsai, Y.H., Liang, P.H., and Wang, A. H.-J. (2003) Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase crystals from Thermotoga maritime and Escherichia Coli. Acta Crystallogr. Sect. D Biol. Crystallogr. 59,2265-2268.