Year Graduated: 2017

Student's Name Thesis Advisor(s) List of Published Papers During Study Time
**Equally Contributing Authors
* Corresponding Author(s)
Mei-Yuan Hsu / 許媄媛 Cheng-Chung Wang
  1. Catalytic Dehydrative Glycosylation. Mei-Yuan Hsu, Sarah Lam, Chia-Hui Wu, Jim-Min Fang, and Cheng-Chung Wang. Submitted to Org. Lett.
  2. Solvent- and work up- free synthesis of 2-deoxyglucosides from glycals. Mei-Yuan Hsu, Yi-Pei Liu, Sarah Lam, Su-Ching Lin and Cheng-Chung Wang Beilstein J. Org. Chem. 2016, 12, 1758–1764.
Chin-Wei Lin / 林津瑋 Chung-Yi Wu
  1. Tsai, T.-I.; Li, S.-T.; Liu, C.-P.; Chen, K. Y.; Shivatare, S. S.; Lin, C.-W.; Liao, S.-F.; Lin, C.-W.; Hsu, T.-L.; Wu, Y.-T.; Tsai, M.-H.; Lai, M.-Y.; Lin, N.-H.; Wu, C.-Y.; Wong, C.-H., An Effective Bacterial Fucosidase for Glycoprotein Remodeling. ACS Chemical Biology 2017, 12 (1), 63-72.
  2. Lin, C.-W.; Tsai, M.-H.; Li, S.-T.; Tsai, T.-I.; Chu, K.-C.; Liu, Y.-C.; Lai, M.-Y.; Wu, C.-Y.; Tseng, Y.-C.; Shivatare, S. S.; Wang, C.-H.; Chao, P.; Wang, S.-Y.; Shih, H.-W.; Zeng, Y.-F.; You, T.-H.; Liao, J.-Y.; Tu, Y.-C.; Lin, Y.-S.; Chuang, H.-Y.; Chen, C.-L.; Tsai, C.-S.; Huang, C.-C.; Lin, N.-H.; Ma, C.; Wu, C.-Y.; Wong, C.-H., A common glycan structure on immunoglobulin G for enhancement of effector functions. Proc. Natl. Acad. Sci. USA 2015, 112 (34), 10611-10616.
  3. Liang, C.-H.; Wang, S.-K.; Lin, C.-W.; Wang, C.-C.; Wong, C.-H.; Wu, C.-Y., Effects of Neighboring Glycans on Antibody–Carbohydrate Interaction. Angew. Chem. Int. Ed. 2011, 50 (7), 1608-1612.
  4. Chang, S.-H.; Han, J.-L.; Tseng, S. Y.; Lee, H.-Y.; Lin, C.-W.; Lin, Y.-C.; Jeng, W.-Y.; Wang, A. H. J.; Wu, C.-Y.; Wong, C.-H., Glycan Array on Aluminum Oxide-Coated Glass Slides through Phosphonate Chemistry. J. Am. Chem. Soc. 2010, 132 (38), 13371-13380.
  5. Wang, C.-C.; Huang, Y.-L.; Ren, C.-T.; Lin, C.-W.; Hung, J.-T.; Yu, J.-C.; Yu, A. L.; Wu, C.-Y.; Wong, C.-H., Glycan microarray of Globo H and related structures for quantitative analysis of breast cancer. Proc. Natl. Acad. Sci. USA 2008, 105 (33), 11661-11666.
  6. Tseng, S. Y.; Wang, C. C.; Lin, C.-W.; Chen, C. L.; Yu, W. Y.; Chen, C. H.; Wu, C. Y.; Wong, C. H., Glycan arrays on aluminum-coated glass slides. Chem Asian J 2008, 3 (8-9), 1395-405.
  7. Chen, H.-W.; Lin, C.-W.; Chen, C.-C.; Yang, L.-B.; Chiang, M.-H.; Liaw, W.-F., Homodinuclear Iron Thiolate Nitrosyl Compounds [(ON)Fe(S,S-C6H4)2Fe(NO)2]- and [(ON)Fe(SO2,S-C6H4)(S,S-C6H4)Fe(NO)2]- with {Fe(NO)}7-{Fe(NO)2}9 Electronic Coupling: New Members of a Class of Dinitrosyl Iron Complexes. Inorg. Chem. 2005, 44 (9), 3226-3232.
Chia-Lin Chen / 陳加林 Che Ma
  1. Chen CL, Hsu JC, Lin CW, Wang CH, Tsai MH, Wu CY, Wong CH, Ma C. (2017) Crystal structure of a homogeneous IgG-Fc glycoform with the N-glycan designed to maximize the antibody dependent cellular cytotoxicity. ACS Chem Biol. (Epub ahead of print, DOI: 10.1021/acschembio.7b00140.)
  2. Lee CP, Chiang SL, Ko AM, Liu YF, Ma C, Lu CY, Huang CM, Chang JG, Kuo TM, Chen CL, Tsai EM, Ko YC. (2016) ALPK1 phosphorylates myosin IIA modulating TNF-α trafficking in gout flares. Sci Rep. 6:25740.
  3. Lin CW, Tsai MH, Li ST, Tsai TI, Chu KC, Liu YC, Lai MY, Wu CY, Tseng YC, Shivatare SS, Wang CH, Chao P, Wang SY, Shih HW, Zeng YF, You TH, Liao JY, Tu YC, Lin YS, Chuang HY, Chen CL, Tsai CS, Huang CC, Lin NH, Ma C, Wu CY, Wong CH. (2015) A common glycan structure on immunoglobulin G for enhancement of effector functions. Proc Natl Acad Sci U S A. 112(34):10611-6.
  4. Wu HH, Hwang-Verslues WW, Lee WH, Huang CK, Wei PC, Chen CL, Shew JY, Lee EY, Jeng YM, Tien YW, Ma C, Lee WH. (2015) Targeting IL-17B-IL-17RB signaling with an anti-IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines. J Exp Med. 212(3):333-49
  5. Wang YL, Lin YT, Chen CL, Shaw GC, Liaw SH. (2014) Crystallization and preliminary crystallographic analysis of poly(3-hydroxybutyrate) depolymerase from Bacillus thuringiensis. Acta Crystallogr F Struct Biol Commun. 70(Pt 10):1421-3.
  6. Kung CC, Naik MT, Wang SH, Shih HM, Chang CC, Lin LY, Chen CL, Ma C, Chang CF, Huang TH. (2014) Structural analysis of poly-SUMO chain recognition by the RNF4-SIMs domain. Biochem J. 462(1):53-65.
  7. Huang CK, Yang CY, Jeng YM, Chen CL, Wu HH, Chang YC, Ma C, Kuo WH, Chang KJ, Shew JY, Lee WH. (2013) Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-κB-mediated antiapoptotic pathway. Oncogene 33(23) 2968-77
Su Tsung-Wei / 蘇琮為 Su-Chang Lin
  1. 1. Kao, W. P., C. Y. Yang, T. W. Su, Y. T. Wang, Y. C. Lo and S. C. Lin (2015). "The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-kappaB signaling." Apoptosis 20(2): 174-195.
  2. Lin, S. M., S. C. Lin, J. Y. Hong, T. W. Su, B. J. Kuo, W. H. Chang, Y. F. Tu and Y. C. Lo (2017). "Structural Insights into Linear Tri-ubiquitin Recognition by A20-Binding Inhibitor of NF-kappaB, ABIN-2." Structure 25(1): 66-78.
  3. 3. Su, T. W., C. Y. Yang, W. P. Kao, B. J. Kuo, S. M. Lin, J. Y. Lin, Y. C. Lo and S. C. Lin (2017). "Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome." Structure 25(3): 407-420.
Shih-Che Lin / 林士哲 Rong-Jie Chein

"Total Synthesis of the Labdane Diterpenes Galanal A and B from Geraniol" Shih-Che Lin, Rong-Jie Chein. J. Org. Chem. 2017, 82, 1575?1583.

Mapatuna Gamage Asitha Namal Perera / 皮瑞拉 Shih-Hsiung Wu
  1. Namal Perera, Feng-Ling Yang, Ching-Ming Chang, Yueh-Tung Lu, Shih-Hao Zhan, Yi-Ting Tsai, Jung-Feng Hsieh, Lan-Hui Li, Kuo-Feng Hua, Shih-Hsiung Wu (2017). Galactomannan from Antrodia cinnamomea enhances the phagocytic activity of macrophages. Organic Letters,19 (13), 3486–3489
  2. Namal Perera, Feng-Ling Yanga, Jeffy Cherna, Hsiao-Wen Chiu, Chih-Yu Hsieh, Lan Hui Li, Yan-Long Zhang, Kuo-Feng Huah, Shih-Hsiung Wu (2018). Carboxylic and O-acetyl moieties are essential for the immunostimulatory activity of glucuronoxylomannan: a novel TLR4 specific immunostimulator from Auricularia auricula-judae
  3. Perera N, Yang FL, Lu YT, Li LH, Hua KF, Wu SH. (2018) Antrodia cinnamomea Galactomannan Elicits Immunostimulatory Activity Through Toll-like Receptor 4. Int J Biol Sci 14(10):1378-1388. doi:10.7150/ijbs.24564. Available from